NH51A-1861
Understanding scale dependency of climatic processes with diarrheal disease

Friday, 18 December 2015
Poster Hall (Moscone South)
Fariborz Nasr Azadani1, Antarpreet Jutla1, Ali S Akanda2 and Rita R Colwell3, (1)West Virginia University, Morgantown, WV, United States, (2)University of Rhode Island, Kingston, RI, United States, (3)University of Maryland College Park, Centre for Bioinformatics and Computational Biology, College Park, MD, United States
Abstract:
The issue of scales in linking climatic processes with diarrheal diseases is perhaps one of the most challenging aspect to develop any predictive algorithm for outbreaks and to understand impacts of changing climate. Majority of diarrheal diseases have shown to be strongly associated with climate modulated environmental processes where pathogens survive. Using cholera as an example of characteristic diarrheal diseases, this study will provide methodological insights on dominant scale variability in climatic processes that are linked with trigger and transmission of disease. Cholera based epidemiological models use human to human interaction as a main transmission mechanism, however, environmental conditions for creating seasonality in outbreaks is not explicitly modeled. For example, existing models cannot create seasonality, unless some of the model parameters are a-priori chosen to vary seasonally. A systems based feedback approach will be presented to understand role of climatic processes on trigger and transmission disease. In order to investigate effect of changing climate on cholera, a downscaling approach using support vector machine will be used. Our preliminary results using three climate models, ECHAM5, GFDL, and HADCM show that varying modalities in future cholera outbreaks.